4.5 Review

The thalamus is more than just a relay

Journal

CURRENT OPINION IN NEUROBIOLOGY
Volume 17, Issue 4, Pages 417-422

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2007.07.003

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Funding

  1. NEI NIH HHS [R01 EY003038, EY03038, R01 EY003038-29] Funding Source: Medline
  2. NIDCD NIH HHS [R01 DC008794-02, R01 DC008794, DC008794] Funding Source: Medline

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The lateral geniculate nucleus and pulvinar are examples of two different types of relay: the former is a first order relay, transmitting information from a subcortical source (retina), while the latter is mostly a higher order relay, transmitting information from layer 5 of one cortical area to another cortical area. First and higher order thalamic relays can also be recognized for much of the rest of thalamus, and most of thalamus seems to be comprised of higher order relays. Higher order relays seem especially important to general corticocortical communication, and this challenges and extends the conventional view that such communication is based on direct corticocortical connections.

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