Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 396, Issue 1, Pages 315-325Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-009-3274-y
Keywords
Clays; Layered double hydroxides; Enzymes; Modified electrodes; Biosensors
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Two-dimensional layered inorganic solids, such as cationic clays and layered double hydroxides (LDHs), also defined as anionic clays, have open structures which are favourable for interactions with enzymes and which intercalate redox mediators. This review aims to show the interest in clays and LDHs as suitable host matrices likely to immobilize enzymes onto electrode surfaces for biosensing applications. It is meant to provide an overview of the various types of electrochemical biosensors that have been developed with these 2D layered materials, along with significant advances over the last several years. The different biosensor configurations and their specific transduction procedures are discussed.
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