4.7 Article

β-cyclodextrin-catalyzed monosulfonylation of amines and amino acids in water

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 349, Issue 11-12, Pages 1873-1876

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200600652

Keywords

amines; amino acids; beta-cyclodextrin; sulfonamides; sulfonyl chlorides; water

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A mild and efficient procedure has been developed for the first time under biomimetic conditions for the monosulfonylation of various amines and amino acids catalyzed by P-cyclodextrin in water at room temperature to afford the corresponding sulfonamides in high yields.

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