Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 396, Issue 3, Pages 973-982Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-009-2996-1
Keywords
Nanoparticle; NMR; FTIR; MS; XPS; Combustion elemental analysis
Funding
- Shandong University, St. Jude Children's Research Hospital
- American Lebanese Syrian Associated Charities (ALSAC)
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Chemical modifications of nanoparticle (NP) surfaces are likely to regulate their activities, remove their toxic effects, and enable them to perform desired functions. It is urgent to develop analytical strategies for acquiring structural and quantitative information about small molecules linked to the surface of NP. Recent progress in characterizing the surface chemistry of NPs using nuclear magnetic resonance (NMR) spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, liquid chromatography-mass spectroscopy (LC-MS), X-ray photoelectron spectroscopy (XPS), and combustion elemental analysis are reviewed.
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