4.6 Article

Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes

Journal

MICROBES AND INFECTION
Volume 9, Issue 10, Pages 1156-1166

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ELSEVIER
DOI: 10.1016/j.micinf.2007.05.003

Keywords

leucine-rich repeat; pathogenicity; surface proteins; virulence factors; invasins

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The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich repeats known as internalins (Inl). The generation of novel mutants and comparative analysis of Inl variability among Listeria and other bacterial genomes suggest that beyond the extensively- studied invasins, InlA and InlB, additional internalins also play important functions in the infectious process. (C) 2007 Elsevier Masson SAS. All rights reserved.

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