Journal
ACTA PSYCHIATRICA SCANDINAVICA
Volume 116, Issue 2, Pages 129-136Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1600-0447.2007.01008.x
Keywords
executive functions; attention deficit-hyperactivity disorder; neuropsychology; stability
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Funding
- NICHD NIH HHS [5R01 HD-36317-07] Funding Source: Medline
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Objective: Although individuals with attention deficit-hyperactivity disorder (ADHD) commonly exhibit deficits in executive functions that greatly increase the morbidity of the disorder, all available information on the subject is cross sectional. Method: Males (n = 85) 9-22 years with ADHD followed over 7 years into young adulthood were assessed on measures of sustained attention/vigilance, planning and organization, response inhibition, set shifting and categorization, selective attention and visual scanning, verbal and visual learning, and memory. A binary definition of executive function deficits (EFDs) was defined based on a subject manifesting at least two abnormal tests 1.5 standard deviations from controls. Results: The majority of subjects maintained EFDs over time (kappa: 0.41, P < 0.001; sensitivity: 55%, specificity: 85%, positive predictive value: 69%, and negative predictive value: 75%). Conclusion: Considering the morbidity of EFDs, these findings stress the importance of their early recognition for prevention and early intervention strategies. EFDs are stable over time.
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