Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 391, Issue 3, Pages 933-942Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-008-1899-x
Keywords
microfluidics; electric analysis; patch-clamp; flow cytometry; single-cell analysis
Ask authors/readers for more resources
Microfluidics offers an ideal platform to integrate cell-based assays with electric measurements. The technological advances in microfluidics, microelectronics, electrochemistry, and electrophysiology have greatly inspired the development of microfluidic/electric devices that work with a low number of cells or single cells. The applications of these microfluidic systems range from the detecting of cell culture density to the probing of cellular functions at the single-cell level. In this review, we introduce the recent advances in the electric analysis of cells on a microfluidic platform, specifically related to the quantification and monitoring of cells in static solution, on-chip patch-clamp measurement, and examination of flowing cells. We also point out future directions and challenges in this field.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available