In vitro evaluation of the sealing ability of newly developed calcium phosphate-based root canal sealer

This study compared the sealing ability of newly developed calcium phosphate-based root canal sealers (CAPSEAL 1, CAPSEAL 11) with other calcium phosphate-based sealer (Sankin Apatite Root Canal Sealer: SARCS 1, SARCS 111), a resin-based sealer (AH Plus), a ZOE-based sealer (Pulp Canal Sealer EWT), and a calcium hydroxide-based sealer (Sealapex) by using an anaerobic bacterial leakage model with Prevotelia nigrescens during a 90-day observation period (n = 15/group). SARCS I and III had significantly greater leakage with P. nigrescens than all other groups (P < .05). There was no other statistical difference between the sealers. Field emission-scanning electron microscope observations showed that both CAPSEAL I and 11 sealers were well-adapted to the canal wall and infiltrated into the dentinal tubules.