4.8 Article

C-C bond formation via double C-H functionalization: Aerobic oxidative coupling as a method for synthesizing heterocoupled biaryls

Journal

ORGANIC LETTERS
Volume 9, Issue 16, Pages 3137-3139

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol071308z

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Funding

  1. NCRR NIH HHS [P20 RR016457, P20RR016457, P20 RR016457-066760] Funding Source: Medline

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[GRAPHICS] The aerobic oxidative coupling of arenes such as benzofuran and N-substituted indoles with benzene and derivatives thereof is described. The reaction is shown to take place in both inter- and intramolecular scenarios.

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