4.8 Article

Direct lactone formation by using hypervalent Iodine(III) reagents with KBr via selective C-H abstraction protocol

Journal

ORGANIC LETTERS
Volume 9, Issue 16, Pages 3129-3132

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol071315n

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[GRAPHICS] We have developed a new and reliable method for the direct construction of biologically important aryl lactones and phthalides from carboxylic and benzoic acids, using a combination of hypervalent iodine(III) reagents with KBr.

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