Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 72, Issue 16, Pages 6276-6279Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo0708792
Keywords
-
Categories
Ask authors/readers for more resources
A two-step, direct asymmetric synthesis of the trifluoroacetate ammonium salt of boroproline is reported. (-)-Sparteine-mediated lithiation of N-Boc-pyrrolidine afforded N-Boc-aminoboronic acid in good yield and enantioselectivity as determined by HPLC (pinanediol ester). Deprotection using TFA yielded the ammonium salt; full characterization data are presented, and the structure in aqueous solution and the occurrence of a B-N species are discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available