Journal
TETRAHEDRON LETTERS
Volume 48, Issue 33, Pages 5795-5798Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.06.087
Keywords
enaminone; pyrrolizidine; indolizidine
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The formal aza-[3+2] cycloaddition reactions of cyclopropen ones and cyclic enaminones, including a chiral one, were employed for the first time in the direct formation of new pyrrolidine and indolizidine derivatives. The regiochemistry of cyclization is dependent of both ring size and steric factors of enaminones. (c) 2007 Elsevier Ltd. All rights reserved.
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