4.4 Article

Inter and intramolecular copper(I)-catalyzed 1,3-dipolar cycloaddition of azido-alkynes: synthesis of furanotriazole macrocycles

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 33, Pages 5869-5872

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.06.062

Keywords

'click' reaction; macrocycles; 1,3-dipolar cycloaddition

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The Cu(I)-catalyzed cycloaddition of azido-alkynes (click reaction) of furanose sugar substrates provides a facile approach for the construction of macrocyclic molecules via an inter and/or intramolecular cycloaddition based on the functionality between alkyne and azide. (c) 2007 Elsevier Ltd. All rights reserved.

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