Journal
TETRAHEDRON LETTERS
Volume 48, Issue 33, Pages 5755-5759Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.06.090
Keywords
phosphonic acid; H-phosphinic acid; hypophosphorous acid
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Funding
- NIGMS NIH HHS [R01 GM067610-04, R01 GM067610] Funding Source: Medline
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A novel access to phosphonic acids via Pd-catalyzed tandem carbon-phosphorus bond formation-oxidation processes was developed. The procedures involve atom-economical and environmentally friendly functionalization reactions of hypophosphorous acid (H3PO2) and H-phosphinic acids [RP(O)(OH)(H)]. (c) 2007 Elsevier Ltd. All rights reserved.
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