Journal
PSYCHIATRY RESEARCH-NEUROIMAGING
Volume 155, Issue 3, Pages 265-269Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.pscychresns.2007.01.010
Keywords
PTSD; depression; Comorbidity
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Posttraumatic Stress Disorder (PTSD) is thought to involve a dysregulation of medial prefrontal-amygdala activity in response to fear. PTSD studies, however, have been confounded by comorbid depression, which shows similar dysregulation. Amygdala and medial prefrontal activity was reduced in PTSD-depression compared to PTSD-alone samples, highlighting the need to account for comorbidity. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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