Journal
SYNTHESIS-STUTTGART
Volume -, Issue 16, Pages 2576-2580Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-983786
Keywords
thioureas; enones; N-heterocycles; conjugate additions; alkaloids
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The first enantioselective conjugate addition reaction of IH-benzotriazolc with a variety of enones has been developed. The process, catalyzed by a cinchona alkaloid thiourea, affords Michael adducts in good yields and with moderate to good enantioselectivities.
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