Journal
NATURE
Volume 448, Issue 7155, Pages 767-774Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nature05985
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Funding
- Intramural NIH HHS Funding Source: Medline
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At first glance, cancer and ageing would seem to be unlikely bedfellows. Yet the origins for this improbable union can actually be traced back to a sequence of tragic - and some say unethical - events that unfolded more than half a century ago. Here we review the series of key observations that has led to a complex but growing convergence between our understanding of the biology of ageing and the mechanisms that underlie cancer.
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