Journal
ANALYTICA CHIMICA ACTA
Volume 724, Issue -, Pages 54-60Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2012.02.039
Keywords
Fe3O4 nanoparticles; Hydroxylated multi-walled carbon nanotubes; Aconitines; Serum samples
Categories
Funding
- National Natural Science Foundation of China [21075127, 20875095]
Ask authors/readers for more resources
A magnetic carbon nanomaterial for Fe3O4 enclosure hydroxylated multi-walled carbon nanotubes (Fe3O4-EC-MWCNTs-OH) was prepared by the aggregating effect of Fe3O4 nanoparticle on MWCNTs-OH, and combined with high-performance liquid chromatography (HPLC)/diode array detection (DAD) to determine the aconitines (aconitine, hypaconitine and mesaconitine) in human serum samples. Compared with other extraction modes investigated in experiment. Fe3O4-EC-MWCNTs-OH sorbents showed a good affinity to target analytes. Some important parameters that could influence extraction efficiency of aconitines, including the extraction mode, amounts of Fe3O4-EC-MWCNTs-OH, pH of sample solution, extraction time, desorption solvent and desorption time, were optimized. Under optimal conditions, the recoveries of spiked serum samples were between 98.0% and 103.0%; relative standard deviations (RSDs) ranged from 0.9% to 6.2%. The correlation coefficients varied from 0.9996 to 0.9998. The limits of detection ranged from 3.1 ng mL(-1) to 4.1 ng mL(-1) at a signal-to-noise ratio of 3. The experimental results showed that the proposed method was feasible for the analysis of aconitines in serum samples. (C) 2012 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available