4.8 Article

Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 33, Pages 10106-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja0740869

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The crystal structure of a DNA quadruplex, d(TGGGGT), crystallized in the presence of calcium and sodium ions, shows the presence of both ions in the central channel of the structure. This was verified by anomalous dispersion maps, which unequivocally showed the presence of calcium ions.

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