Journal
ORGANIC LETTERS
Volume 9, Issue 18, Pages 3519-3521Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0713537
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N-Heterocyclic carbene (NHC) has been employed as an efficient catalyst for ring expansion of 4-formyl-beta-lactams, allowing the facile synthesis of succinimide derivatives. This organocatalytic process features readily availability of the catalyst, low catalyst loading, and mild reaction conditions.
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