Journal
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 104, Issue 3, Pages 241-243Publisher
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1263/jbb.104.241
Keywords
high-throughput screening; cell surface engineering; molecular display; microchamber; yeast cell chip; single cell
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To demonstrate the practical use of a novel high-throughput screening system by a single cell reaction for the rapid screening of combinatorially mutated beta-glucosidase 1 from Aspergillus oryzae, a yeast cell chip microchamber array in combination with yeast cell surface engineering was successfully developed.
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