Journal
AMERICAN JOURNAL OF MEDICINE
Volume 120, Issue 9, Pages 764-768Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjmed.2006.12.013
Keywords
antibody deficiency; common variable immunodeficiency; failure to thrive; hypogammaglobulinemia; immune deficiency; opportunistic organisms; recurrent infections
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Several primary immunodeficiencies may have their initial presentation in adulthood. Although recurrent infections are the hallmark of an underlying immunodeficiency, they need not be the presenting manifestation. This review highlights aspects of infections, as well as noninfectious diseases, that should prompt a high index of suspicion for an underlying immune disorder. The office tests that can be obtained for initial screening and their interpretation are detailed. (C) 2007 Elsevier Inc. All rights reserved.
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