4.5 Article

Fixed and random effects selection in linear and logistic models

Journal

BIOMETRICS
Volume 63, Issue 3, Pages 690-698

Publisher

WILEY
DOI: 10.1111/j.1541-0420.2007.00771.x

Keywords

Bayesian model selection; logistic regression; mixed effects model; model averaging; parameterexpansion; random effects; variance components test; variable selection

Funding

  1. Intramural NIH HHS Funding Source: Medline

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We address the problem of selecting which variables should be included in the fixed and random components of logistic mixed effects models for correlated data. A fully Bayesian variable selection is implemented using a stochastic search Gibbs sampler to estimate the exact model-averaged posterior distribution. This approach automatically identifies subsets of predictors having nonzero fixed effect coefficients or nonzero random effects variance, while allowing uncertainty in the model selection process. Default priors are proposed for the variance components and an efficient parameter expansion Gibbs sampler is developed for posterior computation. The approach is illustrated using simulated data and an epidemiologic example.

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