4.6 Article

A nanobody-based electrochemiluminescent immunosensor for sensitive detection of human procalcitonin

Journal

ANALYST
Volume 139, Issue 15, Pages 3718-3721

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an00626g

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Funding

  1. National Basic Research Program of China [2010CB732400]
  2. National Natural Science Foundation of China [31071146, 31271365, 21175021]
  3. Natural Science Foundation of Jiangsu Province [BK2011599]
  4. Excellent Young Teachers Program of Southeast University [3231001201]
  5. Fundamental Research Funds for the Central Universities

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The development of a nanobody-based electrochemiluminescent immunosensor for procalcitonin quantification is described. A highly specific and enhanced sensitivity of target detection was achieved by CdTe quantum dot encapsulated silica nanoparticle-assisted signal amplification.

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