Journal
ANALYST
Volume 139, Issue 21, Pages 5367-5374Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4an01208a
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Funding
- Institute of Chemical Biology - UK Engineering and Physical Sciences Research Council [EP/C54269X/1, EP/I017887/1]
- Human Frontier Science Program [RGP0061/2011]
- EPSRC [EP/I017887/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/I017887/1] Funding Source: researchfish
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Addressable droplet microarrays are potentially attractive as a way to achieve miniaturised, reduced volume, high sensitivity analyses without the need to fabricate microfluidic devices or small volume chambers. We report a practical method for producing oil-encapsulated addressable droplet microarrays which can be used for such analyses. To demonstrate their utility, we undertake a series of single cell analyses, to determine the variation in copy number of p53 proteins in cells of a human cancer cell line.
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