Journal
JOURNAL OF NEURAL TRANSMISSION
Volume 114, Issue 9, Pages 1167-1171Publisher
SPRINGER WIEN
DOI: 10.1007/s00702-007-0725-5
Keywords
substantia nigra hyperechogenicity; vulnerability marker; Parkinson's disease; genetic predisposition
Categories
Ask authors/readers for more resources
Hyperechogenicity of the substantia nigra (SN) has been proposed to be a typical finding in Parkinson's disease (PD) and a marker of vulnerability to nigrostriatal dysfunction in healthy subjects. This large cross-sectional study including 1120 subjects older than 50 years without any signs of PD was performed to evaluate the association of SN hyperechogenicity and other proposed epidemiological risk factors for PD. Among all variables assessed only family history of PD and male gender proved to be significantly associated with SN hyperechogenicity, indicating a genetic predisposition for the ultrasound marker.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available