4.8 Article

Convergent extension and the hexahedral cell

Journal

NATURE CELL BIOLOGY
Volume 9, Issue 9, Pages 1010-1015

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ncb438

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Funding

  1. Medical Research Council [G0601131] Funding Source: Medline
  2. NICHD NIH HHS [HD044750, R01 HD044750, R01 HD044750-03] Funding Source: Medline

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During development, embryonic cells sculpt three-dimensional tissues. Although cell polarity is commonly analysed along one, and sometimes two, dimensions, this perspective illustrates how higher-order cell polarity regulates convergent extension-the coordinated cell rearrangement that produces solid tissue elongation.

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