Coxiella burnetii infection of aortic aneurysms grafts:: report of 30 new cases and evaluation or vascular of outcome

Q fever is a zoonotic disease caused by Coxiella burnetii. Polymorphic, the disease may present as an acute or chronic infection. Vascular infections are the second most common form of chronic Q fever, following endocarditis. Herein, we studied the outcome of 30 new cases of aortic infection caused by C. burnetii using uni- and multivariate analyses. The outcome of ten cases previously reported by our tearn was also updated. Of these 40 patients, 32 had a follow-up of >= 3 years. Among them, the overall mortality was of 25% (8/32). Vascular rupture was sianificantly and independently (multivariate P=0.03) associated with a lethal issue, whereas vascular surgery was significantly associated with recovery (uni- and multivariate P < 0.01). Our findings demonstrate the critical importance of surgery in the management of C. burnetii vascular infections.