4.6 Article

Logic gates for multiplexed analysis of Hg2+ and Ag+

Journal

ANALYST
Volume 137, Issue 11, Pages 2687-2691

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2an35180c

Keywords

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Funding

  1. National Basic Research Program of China [2010CB732403]
  2. National Nature Sciences Funding of China [20905013, 41076059]
  3. Program for New Century Excellent Talents in Fujian Province University [JA10011]

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The design of devices with multiple functions, simple handling procedures and sufficient sensitivity has drawn great interests in the field of analysis. Metal-nucleotide based pairs, such as T-Hg2+-T and C-Ag (+)-C complexes accompanied by SYBR Green I (SG), are used to selectively bind duplex-strand DNA by observing a bright fluorescence signal in this work, thus yielding a simple method for the rapid detection of Hg2+ and Ag+ without a complex labeling process. Based on this principle, 'OR' and 'AND' logic gates for the multiplexed analysis of Hg2+ and Ag+ were developed, and their practical application for the detection of Hg2+ and Ag+ in drinking water was reported.

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