Journal
ANALYST
Volume 137, Issue 10, Pages 2309-2312Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2an16092g
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Funding
- Ministry of Science and Technology of China [2012ZX09506001-010, 2012CB722605]
- Shenzhen Sci Tech Bureau
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Label-free fluorescent assays were developed based on the competition of intramolecular DNA hybridization and aptamer-target binding. Using small molecule adenosine triphosphate (ATP) and biomacro-molecule thrombin as model targets, our design was proved to be a general method with good sensitivity and high selectivity.
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