Journal
PROTEOMICS
Volume 7, Issue 17, Pages 3051-3054Publisher
WILEY
DOI: 10.1002/pmic.200700224
Keywords
algorithm; bioinformatics; de novo sequencing
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De novo peptide sequencing algorithms are often tested on relatively small data sets made of excellent spectra. Since there are always more and more tandem mass spectra available, we have assembled six large, reliable, and diverse (three mass spectrometer types) data sets intended for such tests and we make them accessible via a web server. To exemplify their use we investigate the performance of Lutefisk, PepNovo, and PepNovoTag, three well-established peptide de novo sequencing programs.
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