Journal
ANALYST
Volume 136, Issue 1, Pages 191-195Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0an00456a
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Funding
- NSFC
- Chinese Academy of Sciences
- State Key Basic Research Program
- NSFC-DFG [TRR61]
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A resorufin derivative with a DBS group (probe 1) was designed and investigated for the detection of acetylcholinesterase (AChE) and inhibitor screening. The new assay is based on cascade enzymatic and chemical reactions of ATC, AChE and probe 1, and it can be carried out in a dual-signal detection mode. Moreover, the results show that probe 1 can be used for cell fluorescence staining.
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