Journal
QUIMICA NOVA
Volume 30, Issue 5, Pages 1100-1103Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422007000500009
Keywords
Casearia sylvestris; clerodane diterpenes; 15-hydroxy-3-cleroden-2-one
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Ethanolic extracts of the leaves of Casearia sylvestris yielded a novel clerodane diterpene, 15-hydroxy-3-cleroden-2-one, together with the known diterpenes (-)-hardwickiie acid, reported for the first time from this species, and casearins B and G, previously isolated from C sylvestris. The structures of all four compounds were determined by spectrometric analysis. The new clerodane diterpene and (-)-hardwickiic acid contain structural features that are completely different from the highly oxygenated casearins and casearvestrins isolated from C sylvestris.
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