4.6 Article

Lysozyme-stabilized gold fluorescent cluster: Synthesis and application as Hg2+ sensor

Journal

ANALYST
Volume 135, Issue 6, Pages 1406-1410

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0an00046a

Keywords

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Funding

  1. U.S. Department of Energy [DE-FG02-08ER64568, DE-FG02-07ER46453, DE-FG02-07ER46471]
  2. National Institute of Health [ES16865]
  3. National Science Foundation [CTS-0120978, CMMI-0749028, DMR-0117792]
  4. NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [R01ES016865] Funding Source: NIH RePORTER

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Highly fluorescent gold clusters have been synthesized in basic aqueous solution by using lysozyme as reducing and stabilizing agents. The lysozyme-stabilized gold fluorescent clusters (LsGFC) have an average size of 1 nm and emission similar to 657 nm. The fluorescence could be specifically quenched by Hg2+, so the LsGFC can be used as a sensor for sensitive and selective Hg2+ detection with a detection limit of 10 nM.

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