Journal
ANALYST
Volume 135, Issue 5, Pages 837-844Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b919584j
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Funding
- National Research Foundation of Korea [R11-2009-044-1002-0, K20904000004-09A050000410]
- KRIBB Research Initiative Program
- Ministry of Knowledge Economy (MKE)
- Korea Industrial Technology Foundation (KOTEF)
- RCUK
- EPSRC [EP/D048664/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/D048664/1] Funding Source: researchfish
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We report recent progress in the development of surface-enhanced Raman scattering (SERS)-based optofluidic platforms for the fast and sensitive detection of chemical and biological analytes. In the current context, a SERS-based optofluidic platform is defined as an integrated analytical device composed of a microfluidic element and a sensitive Raman spectrometer. Optofluidic devices for SERS detection normally involve nanocolloid-based microfluidic systems or metal nanostructure-embedded microfluidic systems. In the current review, recent advances in both approaches are surveyed and assessed. Additionally, integrated real-time sensing systems that combine portable Raman spectrometers with microfluidic devices are also reviewed. Such real-time sensing systems have significant utility in environmental monitoring, forensic science and homeland defense applications.
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