Journal
ANALYST
Volume 134, Issue 9, Pages 1745-1750Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b909080k
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Funding
- National Science Foundation (NSF) [EEC-0304097]
- AFOSR [FA9550-06-1-0021]
- NSF CAREER [BES 044379]
- Robert A. Welch Foundation [C-1220]
- Multidisciplinary University Research Initiative (MURI) [W911NF-04-01-0203]
- Keck Center Nanobiology Training Program of the Gulf Coast Consortia
- NIH [1 T90 DK070121-01]
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [T90DK070121] Funding Source: NIH RePORTER
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Nanoshells are optically tunable core-shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.
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