Journal
ANALYST
Volume 134, Issue 9, Pages 1822-1825Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b908018j
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [20605019, 20873134]
- University of Science and Technology of China
- Chinese Academy of Sciences
- PCSIRT [IRT0756]
Ask authors/readers for more resources
A sensitive and fully DNA-structured ion sensor was built by integrating polyT sequences for highly selective Hg2+ recognitions and two flanking G-quadruplex halves for allosteric signal transductions. The construction of this sensor was very easy that allowed a cost-effective detection of Hg2+ with a limit of detection of 4.5 nM, which was lower than the 10 nM toxic level for drinkable water as regulated by the US's EPA. The strategy employed for the construction of this sensor may be further extended to other sensors through a rational structural fusion between re-engineered aptameric and enzymic DNA sequences.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available