Journal
FEBS LETTERS
Volume 581, Issue 22, Pages 4165-4171Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.febslet.2007.07.046
Keywords
ATP-grasp fold; inositol polyphosphate kinase; arabidopsis
Funding
- Biotechnology and Biological Sciences Research Council [BB/C514090/1] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [BB/C514090/1] Funding Source: Medline
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The Arabidopsis genome encodes a family of inositol 1,3,4-trisphosphate 5/6-kinases which form a subgroup of a larger group of ATP-grasp fold proteins. An analysis of the inositol 1,3,4-trisphosphate 5/6-kinase family might, ultimately, be best rewarded by detailed comparison of related enzymes in a single genome. The enzyme encoded by At2G43980, AtITPK4; is an outlier to its family. At2G43980 is expressed in male and female organs of young and mature flowers. AtITPK4 differs from other family members in that it does not display inositol 3,4,5,6-tetrakisphosphate 1-kinase activity; rather, it displays inositol 1,4,5,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate isomerase activity. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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