Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 15, Issue 18, Pages 6012-6017Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2007.06.049
Keywords
thiazolidine-2,4-diones; thiazole derivatives; antimicrobial activity; single-x-ray structure
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In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and Vla-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms. (c) 2007 Elsevier Ltd. All rights reserved.
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