Journal
CELL CYCLE
Volume 6, Issue 18, Pages 2246-2251Publisher
TAYLOR & FRANCIS INC
DOI: 10.4161/cc.6.18.4739
Keywords
ribosome; rRNA; translation; mRNA; protein
Categories
Funding
- NIGMS NIH HHS [GM61725, R01 GM078071-01A1, R01 GM061725, R01 GM078071, GM078071] Funding Source: Medline
- NINDS NIH HHS [R01 NS039837, NS39837] Funding Source: Medline
Ask authors/readers for more resources
The ribosome filter hypothesis postulates that ribosomes are not simply translation machines but also function as regulatory elements that differentially affect or filter the translation of particular mRNAs. On the basis of new information, we take the opportunity here to review the ribosome filter hypothesis, suggest specific mechanisms of action, and discuss recent examples from the literature that support it.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available