4.4 Article

N-Dimethylphosphoryl-protection in the efficient synthesis of glucosamine-containing oligosaccharides with alternate N-acyl substitutions

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 39, Pages 7049-7052

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.07.108

Keywords

dimetbylpbosphoryl; protecting group; glucosamine; acylation; oligosaccharidee

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Ready transformation of N-dimethylphosphoryl-protection into the corresponding N-acyl derivatives (in the presence of acyl chlorides and DMAP in pyridine) provided an effective approach to the synthesis of glucosamine-containing oligosaccharides with alternate N-acyl substitutions. (C) 2007 Elsevier Ltd. All rights reserved.

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