4.4 Article

A rapid synthesis of 3-sulfenyl indoles using Selectfluor™

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 39, Pages 7034-7037

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.07.130

Keywords

thiolation; indoles; thiols; 3-arylthioindoles

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The direct 3-arylthiolation of indoles with aromatic thiols has been achieved in the presence of Selectfluor (TM) under mild conditions to produce 3-arylthioindoles in relatively good to excellent yields and with high selectivity. This method is effective even with 2-unsubstituted indoles. (c) 2007 Published by Elsevier Ltd.

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