Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 72, Issue 20, Pages 7650-7655Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo0712603
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[GRAPHICS] A new and efficient method for the synthesis of 2,3,6-trisubstituted imidazo[1,2-a]pyridine derivatives using a microwave-assisted one-pot, two-step Suzuki/heteroarylation or one-pot, three-step cyclization/Suzuki/heteroarylation was developed. Polysubstituted compounds are obtained in good yield from 2-amino-5-halogenopyridines, 2-halogenocarbonyl derivatives, boronic acids, and heteroaryl bromides.
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