Journal
MOLECULAR & CELLULAR PROTEOMICS
Volume 6, Issue 10, Pages 1771-1777Publisher
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/mcp.M700057-MCP200
Keywords
-
Categories
Funding
- NCI NIH HHS [CA087660, CA37393] Funding Source: Medline
- NHGRI NIH HHS [HG003456] Funding Source: Medline
Ask authors/readers for more resources
Activity-based protein profiling has emerged as a valuable technology for labeling, enriching, and assessing protein activities from complex mixtures. This is primarily accomplished via a two-step identification and quantification process. Here we show a highly quantitative and streamlined method, termed catch-and-release activity profiling of enzymes ( CAPE), which reduces this procedure to a single step. Furthermore the CAPE approach has the ability to detect small quantitative changes that may have been missed by alternative mass spectrometry-based techniques.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available