Journal
APPLIED SPECTROSCOPY
Volume 61, Issue 10, Pages 1123-1127Publisher
SOC APPLIED SPECTROSCOPY
DOI: 10.1366/000370207782217770
Keywords
spatially offset Raman spectroscopy; SORS; Raman spectroscopy; diffuse scattering; turbid media; pharmaceutical products
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Funding
- EPSRC [EP/D037662/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/D037662/1] Funding Source: researchfish
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A simple procedure for the recovery of deep subsurface Raman spectra in stratified turbid samples by defocusing a conventional Raman instrument is presented. The method is based on effects present with spatially offset Raman spectroscopy (SORS) and, although not as efficient as the standard SORS approach, it permits a simple way of recovering subsurface Raman spectra from less challenging samples. Demonstration of the effect is performed using a standard SORS device and a commercial Raman instrument on the noninvasive measurement of paracetamol tablets held within a nontransparent white plastic bottle.
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