4.2 Article

Persons living with HIV/AIDS: factors associated with adherence to antiretroviral treatment

Journal

CADERNOS DE SAUDE PUBLICA
Volume 23, Issue 10, Pages 2305-2316

Publisher

CADERNOS SAUDE PUBLICA
DOI: 10.1590/S0102-311X2007001000006

Keywords

highly active antiretroviral therapy; acquired immunodeficiency syndrome; HIV

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This study aimed to describe the adherence of persons living with HIV/AIDS to antiretroviral therapy (ART) and to investigate adherence predictors among the following: level of schooling, presence of side effects, current or previous interruption of ART by the persons themselves, self-esteem, self-efficacy expectation, coping strategies, social support, and satisfaction with the health professional-patient relationship. Adherence was measured by self-reported number of ART pills/capsules missed during the previous week and previous month, evaluated as satisfactory when less than 5%. 101 HIV+ adults took part in this study, 60.4% males, ranging from 20 to 71 years of age (mean = 37.9 years), and 73.3% symptomatic. Data procedures included interviews and the use of validated instruments. The majority of participants (n = 73; 72.3%) reported adherence of >= 95%. Logistic regression showed that a history of self-reported ART interruption and self-efficacy expectations were significant adherence predictors. Upgrading of care with interdisciplinary teams is needed to develop an appropriate approach to the medical and psychosocial difficulties of ART adherence by persons with HIV/AIDS.

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