Journal
RADIATION PHYSICS AND CHEMISTRY
Volume 76, Issue 10, Pages 1577-1586Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.radphyschem.2007.01.002
Keywords
aging; anti-aging; oxygen stress; free radicals; DNA-mutation
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The present review deals with some factors determining the anti-aging as well as the aging process. In order to get a deeper insight in the subject matter, firstly some less known spectroscopic and kinetic data of antioxidant vitamins (C, E, beta-carotene) acting as anti-aging factors by electron transfer are briefly discussed. The generation of oxygen transients (OH, ROO center dot, O-1(2), ozone radicals, etc.) by sunlight, ultrasonic and microwave radiation are causing '' oxygen stress '' and contribute to early ageing is also reviewed. Particular attention is paid to external environmental aging factors. Their action is based on the incorporation of various pollutants contained in water and air in the human organism. In this respect the polycyclic aromatic hydrocarbons (PAHs) play an essential role by initiating DNA-mutation, leading to an accelerate aging, carcinogenesis and diseases. (c) 2007 Elsevier Ltd. All rights reserved.
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