Journal
CURRENT OPINION IN LIPIDOLOGY
Volume 18, Issue 5, Pages 483-491Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOL.0b013e3282a66099
Keywords
aortic valve stenosis; calcification; inflammation; valvular heart disease
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Recent findings regarding the interaction of inflammatory cells, lipids, mediators of calcification, and renin-angiotensin system in stenotic valves support the current opinion of aortic valve stenosis being an actively regulated disease, potentially amenable to targeted molecular therapy. Evidence from prospective clinical studies is eagerly awaited.
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