Thermotherapy using magnetic nanoparticles

Thermotherapy using magnetic nanoparticles, also termed nanotherapy, is a new therapeutic concept. Tumor cells are damaged by local application of heat. This method comprises direct injection of a magnetic fluid into the tumor and its subsequent heating in an alternating magnetic field. Depending on the applied temperature and the duration of heating, the therapy either results in direct death of tumor cells or makes the cells more susceptible to concomitant radiotherapy or chemotherapy. The results of three feasibility studies for the treatment of glioblastoma, prostate cancer, and esophageal cancer are presented.