Journal
TRENDS IN GENETICS
Volume 23, Issue 10, Pages 521-529Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2007.08.004
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- NLM NIH HHS [5 P41 LM06252-09] Funding Source: Medline
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Rolling-circle eukaryotic transposons, known as Helitron transposons, were first discovered in plants (Arabidopsis thaliana and Oryza sativa) and in the nematode Caenorhabditis elegans. To date, Helitrons have been identified in a diverse range of species, from protists to mammals. They represent a major class of eukaryotic transposons and are fundamentally different from classical transposons in terms of their structure and mechanism of transposition. Helitrons seem to have a major role in the evolution of host genomes. They frequently capture diverse host genes, some of which can evolve into novel host genes or become essential for helitron transposition.
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